Supo® Aromasin 25mg

Key Information about Supo Aromasin 25 (Exemestane):

• Primary Use:
  Supo Aromasin 25 (Exemestane), marketed under the brand name Aromasin, is a third-generation aromatase inhibitor (AI) used primarily in the treatment of breast cancer in postmenopausal women. It is also commonly used in the bodybuilding and anabolic steroid community to prevent estrogenic side effects during steroid cycles. Aromasin works by irreversibly inhibiting the aromatase enzyme, which is responsible for converting androgens (e.g., testosterone) into estrogen. By reducing estrogen levels, Aromasin helps prevent estrogenic side effects like gynecomastia (male breast tissue development) and water retention during anabolic steroid cycles.
• Mechanism of Action:
  Aromasin works by irreversibly binding to the aromatase enzyme, blocking its ability to convert androgens (such as testosterone and androstenedione) into estrogens. This decreases overall estrogen levels in the body, which can be beneficial during anabolic steroid cycles that involve compounds with high aromatization potential (e.g., Testosterone, Nandrolone, Dianabol). By reducing estrogen levels, Aromasin also lowers the risk of estrogenic side effects, including gynecomastia and water retention.
• Common Uses:
  • Estrogen Control During Steroid Cycles: Aromasin is widely used by bodybuilders and athletes during cycles of aromatizable steroids (steroids that convert to estrogen) to prevent estrogen-related side effects. This includes gynecomastia, water retention, and fat gain.
  • Post Cycle Therapy (PCT): Aromasin is sometimes included in PCT protocols to help manage estrogen rebound and restore natural hormone production after anabolic steroid use. After discontinuing anabolic steroids, estrogen levels can rise, leading to potential side effects like fat gain or the return of gynecomastia, which Aromasin helps to prevent.
  • Breast Cancer Treatment (Women): Aromasin is primarily prescribed for the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is used to lower estrogen levels in the body, as estrogen can fuel the growth of some types of breast cancer.
• Dosing Guidelines:
  • Men (Steroid Cycles):
    • The typical dose for Aromasin during an anabolic steroid cycle is 12.5mg to 25mg per day. The dose is often adjusted based on the aromatization potential of the steroids being used and individual response. Higher doses are usually used when heavier aromatizable steroids like Testosterone or Dianabol are involved.
    • PCT (Post-Cycle Therapy): Aromasin is sometimes used in PCT to help control estrogenic rebound and minimize the risk of gynecomastia and water retention. A typical dose is 12.5mg to 25mg per day, used for 2-4 weeks after the steroid cycle.
  • Women (Breast Cancer Treatment):
    • The typical dose for Aromasin in the treatment of breast cancer is 25mg per day, taken once daily. This is often prescribed for postmenopausal women to reduce the risk of cancer recurrence.
• Side Effects:
  • Joint Pain and Stiffness: Aromasin can cause joint pain, stiffness, and general muscle discomfort. These side effects may be more pronounced in people who already experience joint issues.
  • Fatigue and Weakness: Some users report feeling fatigued, lethargic, or weak, particularly at higher doses or during long-term use.
  • Hot Flashes: Similar to other aromatase inhibitors, hot flashes can occur, especially during higher doses or extended use.
  • Bone Health: Since Aromasin reduces estrogen levels, it may lead to a decrease in bone mineral density over time, potentially increasing the risk of osteoporosis. This is especially a concern for women taking Aromasin long-term for breast cancer treatment.
  • Cholesterol Imbalance: Aromasin can lower HDL (good cholesterol) and increase LDL (bad cholesterol), which may increase the risk of cardiovascular issues, particularly with prolonged use.
  • Liver Stress: Although not as hepatotoxic as oral steroids, Aromasin can still cause mild liver enzyme elevations in some individuals. Regular monitoring of liver function is advised for those using Aromasin alongside other compounds that affect liver health.
  • Nausea and Vomiting: Some users may experience nausea, especially when first starting Aromasin or adjusting doses.
• Cycle Length:
  • Steroid Cycles: Aromasin is typically used throughout the entire steroid cycle to prevent estrogenic side effects. It may also be used for a few weeks during PCT to help manage estrogen rebound.
  • PCT (Post Cycle Therapy): Aromasin is often included in PCT protocols, with a standard duration of 2-4 weeks, usually at a dose of 12.5mg to 25mg per day.
  • Breast Cancer Treatment (Women): When used for breast cancer, Aromasin is often taken for a prolonged period (up to 5 years), but the dose typically remains at 25mg daily.
• Post Cycle Therapy (PCT):
  • Aromasin is sometimes used in PCT to manage estrogen rebound after a cycle of anabolic steroids. When steroids are discontinued, estrogen levels can rise, which can trigger side effects like water retention, fat gain, and the re-emergence of gynecomastia. Aromasin works to lower estrogen levels and reduce these risks.
  • Typical PCT Protocol: Aromasin is often combined with other medications like Clomid or Nolvadex in PCT protocols to restore natural testosterone production and prevent estrogenic side effects. A common PCT dosing strategy may include Aromasin 12.5mg/day combined with Clomid or Nolvadex for 3-4 weeks.
• Stacking:
  • With Testosterone and Other Aromatizable Steroids: Aromasin is commonly stacked with Testosterone, Dianabol, Nandrolone, and other aromatizable steroids to prevent estrogenic side effects such as gynecomastia, water retention, and fat gain.
  • With Other AIs (Aromatase Inhibitors): Aromasin can be stacked with other aromatase inhibitors, such as Arimidex (Anastrozole) or Letrozole, to provide more aggressive estrogen control during steroid cycles. However, this should be done cautiously to avoid excessive suppression of estrogen, which can lead to joint issues, bone density loss, and other negative side effects.
  • With SERMs (Selective Estrogen Receptor Modulators): Aromasin can be used alongside SERMs (like Nolvadex or Clomid) in PCT to restore natural testosterone production and prevent estrogenic side effects from fluctuating hormone levels.

Notes:

• Estrogen Control: Aromasin is considered one of the strongest aromatase inhibitors and is more effective at lowering estrogen levels compared to Arimidex and Letrozole. However, excessive estrogen suppression can lead to side effects like joint pain, mood swings, and bone density loss. It is important to monitor estrogen levels when using Aromasin to ensure a healthy hormonal balance.
• Bone Health Monitoring: Prolonged use of Aromasin, especially at high doses, can increase the risk of osteoporosis and bone fractures. Regular monitoring of bone density may be necessary for long-term users.
• Cholesterol Monitoring: Aromasin can negatively impact cholesterol levels by lowering HDL (good cholesterol) and raising LDL (bad cholesterol). It is important to monitor lipid profiles and adjust diet or supplements as needed to maintain cardiovascular health.